The Cell Cycle Ontology (CCO) has the aim to provide a 'one stop shop' for scientists interested in the biology of the cell cycle that would like to ask questions from a molecular and/or systems perspective: what are the genes, proteins, and so on involved in the regulation of cell division? How do they interact to produce the effects observed in the regulation of the cell cycle? To answer these questions, the CCO must integrate a large amount of knowledge from (...) diverse sources; the irregularity and incompleteness of this information suggests an ontology can act as the means of this integration. The volatility and continued expansion of biological knowledge means the content and modelling of the CCO will have to be frequently changed and updated. The CCO is generated from the input data automatically once every two months. This makes it easy to change the representation to enable certain queries; incorporate new knowledge; and consistently apply design patterns across the CCO. The automatic process also allows the CCO to be delivered in a variety of representations that suit the needs of various CCO customers and the abilities of existing toolsets. In this paper we present the CCO and its characteristics of utility and flexibility, that, from our perspective, make it a beautiful ontology. (shrink)

Do our lives have meaning? Should we create more people? Is death bad? Should we commit suicide? Would it be better if we were immortal? Should we be optimistic or pessimistic? Life, Death, and Meaning brings together key readings, primarily by English-speaking philosophers, on such 'big questions.'.

Do our lives have meaning? Should we create more people? Is death bad? Should we commit suicide? Would it be better to be immortal? Should we be optimistic or pessimistic? Since Life, Death, and Meaning: Key Philosophical Readings on the Big Questions first appeared, David Benatar's distinctive anthology designed to introduce students to the key existential questions of philosophy has won a devoted following among users in a variety of upper-level and even introductory courses.

_First Philosophy: God, Mind, and Freedom_ brings together classic and ground-breaking readings on metaphysics, the philosophy of mind, and the philosophy of religion. Andrew Bailey's highly regarded introductory anthology has been revised and updated in this new edition. The comprehensive introductory material for each chapter and selection remains, and new sections on philosophical puzzles and paradoxes and philosophical terminology have been added. New to this edition are readings from Alvin Plantinga, Frank Jackson, David Chalmers, A.J. Ayer, Bernard Williams, and (...) Thomas Nagel. (shrink)

First Philosophy: God, Mind, and Freedom brings together classic and ground-breaking readings on metaphysics, the philosophy of mind, and the philosophy of religion. Andrew Bailey's highly regarded introductory anthology has been revised and updated in this new edition. The comprehensive introductory material for each chapter and selection remains, and new sections on philosophical puzzles and paradoxes and philosophical terminology have been added. New to this edition are readings from Alvin Plantinga, Frank Jackson, David Chalmers, A.J. Ayer, Bernard Williams, and (...) Thomas Nagel. (shrink)

We show how Berry phase can be used to construct a precision quantum thermometer. An important advantage of our scheme is that there is no need for the thermometer to acquire thermal equilibrium with the sample. This reduces measurement times and avoids precision limitations. We also discuss how such methods can be used to detect the Unruh effect.

Introduction to Philosophy, Fourth Edition, is the most comprehensive topically organized collection of classical and contemporary philosophy available. Building on the exceptionally successful tradition of previous editions, this edition for the first time incorporates the insights of a new coeditor, John Martin Fischer, and has been updated and revised to make it more accessible. Ideal for introductory philosophy courses, the text includes sections on the meaning of life, God and evil, knowledge and reality, the philosophy of science, the mind/body (...) problem, freedom of will, consciousness, ethics, and philosophical puzzles and paradoxes. It presents seventy substantial--and in some cases complete--selections from the best and most influential works in philosophy, offering a unique balance between classical and contemporary material. An extensive glossary of philosophical terms is also included. The fourth edition features fifteen new readings, including work by Albert Camus, Roderick M. Chisholm, Daniel Dennett, Harry G. Frankfurt, William Paley, Derek Parfit, John Perry, Richard Taylor, Peter Van Inwagen, Bernard Williams, and Susan Wolf. Part III, Knowledge and Reality, has been restructured and now includes Plato's Thaetetus, selections by Edmund L. Gettier and Robert Nozick, and an essay by Christopher Grau that explores the philosophical concepts presented in the popular film The Matrix. Two new ethics puzzles--"The Trolley Problem" and "Ducking Harm and Sacrificing Others"--are also included. This edition incorporates Study Questions after each reading and is accompanied by an Instructor's CD and a Student Companion Website, both containing helpful resources. (shrink)

Despite widespread knowledge that fraternity members are frequently involved in the sexual assaults of women, fraternities are rarely studied as social contexts-groups and organizations-that encourage the sexual coercion of women. An analysis of the norms and dynamics of the social construction of fraternity brotherhood reveals the highly masculinist features of fraternity structure and process, including concern with a narrow, stereotypical conception of masculinity and heterosexuality; a preoccupation with loyalty, protection of the group, and secrecy; the use of alcohol as a (...) weapon against women's sexual reluctance; the pervasiveness of violence and physical force; and an obsession with competition, superiority, and dominance. Interfraternity rivalry and competition-particularly over members, intramural sports, and women-encourage fraternity men's commodification of women. We conclude that fraternities will continue to violate women socially and sexually unless they change in fundamental ways. (shrink)

Microgames are rapidly gaining increased attention and are highly being considered because of the technology-based media that enhances students’ learning interests and educational activities. Therefore, this study aims to develop a new construct through confirmatory factor analysis, to comprehensively understand the factors influencing the use of microgames in mathematics class. Participants of the study were the secondary school teachers in West Java, Indonesia, which had a 1-year training in microgames development. We applied a quantitative approach to collect the data via (...) online questionnaires through google form. Structural Equation Modelling with AMOS software was used to analyze the proposed model. Empirical results confirmed the perceived easy to use and subjective norm influence relationship with teachers’ microgame usage behaviors and intentions. In this condition, SN was found to have the initial significant influence on behavioral intention, as attitude, BI, and facilitating conditions also correlated with the actual use of microgames. Furthermore, the largest influential factor was BI, with the results subsequently showing that TPACK had no significant influence on the actual use of microgames. This report is expected to help bridge the gap across several previous studies, as well as contribute to the explanation and prediction of the factors influencing the teachers’ mathematical utilization of the study’s program. Besides this, it also helps to increase the use of microgames in teaching and learning activities. (shrink)

This chapter contains sections titled: Introduction Functional Attribution: Meeting the Explanatory Constraint Functional Attribution: Normativity Postscript: Counterpoint Notes References.

What are the prospects for a cognitive science of meaning? As stated, we think this question is ill posed, for it invites the conflation of several importantly different semantic concepts. In this paper, we want to distinguish the sort of meaning that is an explanandum for cognitive science—something we are going to call meaning—from the sort of meaning that is an explanans in cognitive science—something we are not going to call meaning at all, but rather content. What we are going (...) to call meaning is paradigmatically a property of linguistic expressions or acts: what one’s utterance or sentence means, and what one means by it. What we are going to call content is a property of, among other things, mental representations and indicator signals. We will argue that it is a mistake to identify meaning with content, and that, once this is appreciated, some serious problems emerge for grounding meaning in the sorts of content that cognitive science is likely to provide. (shrink)

We distinguish and review aspects of the history of two models of triage: egalitarian and utilitarian. Egalitarian triage is widely and successfully practiced in battlefield medicine, as well as in the emergency room and the ICU. Utilitarian triage has been sporadically practiced and typically collapses under the pressure of public scrutiny. Unfortunately, the two models tend to be conflated, confusing our understanding of the past and confounding our ability to plan for the future.

The Knowledge Argument of Frank Jackson has not persuaded physicalists, but their replies have not dispelled the intuition that someone raised in a black and white environment gains genuinely new knowledge when she sees colors for the first time. In what follows, we propose an explanation of this particular kind of knowledge gain that displays it as genuinely new, but orthogonal to both physicalism and phenomenology. We argue that Mary’s case is an instance of a common phenomenon in which something (...) new is learned as the result of exploiting representational resources that were not previously exploited, and that this results in gaining genuinely new information. (shrink)

Contains papers presented at the Thirteenth Amsterdam Colloquium in formal semantics, pragmatics and logic, which was held in Amsterdam, December 17-19, 2001.

For the first time, this volume presents a series of critical and constructive studies in the philosophy of J. N. Findlay.

Introducing Philosophy: A Text with Integrated Readings, Tenth Edition is a thorough introduction to the core problems of philosophy, including explanations and background by the authors along with generous excerpts from the philosophers under discussion. Organized topically, the chapters present alternative perspectives-including analytic, continental, feminist, and non-Western viewpoints-alongside the historical works of major philosophers. The text provides the course materials that allow instructors and students to focus on a variety of philosophical problems and perspectives. Spanning 2,500 years, the selections range (...) from the oldest known fragments to cutting-edge contemporary essays. (shrink)

Theories in the behavioral sciences are constrained so that stated relationships are empirically testable and explanations have predictive power. These constraints constitute the classical paradigm, and are trivial just when ?causal relationships? do not hold. It appears that such relationships do not hold for linguistic, and presumably other, behaviors, thus precluding study within the classical paradigm. This compels study of those behaviors in terms of the non?traditional approach to testability and explanation developed in Chomskyan linguistics. These constitute the grammatical paradigm. (...) The existence of two paradigms requires that any inquiry begin by determining which paradigm is appropriate. (shrink)

Bernard Stiegler interviewed by Ben Roberts, Jeremy Gilbert and Mark Hayward.

Professeur de philosophie à l'Université de Lille III, Bernard Jeu (1929-1991) était passionné de sport. Son intérêt n'était pas évènementiel. Ses recherches innovantes, particulièrement sur l'imagiaire, seront encore longtemps précieuses au mouvement sportif dont il était l'un de grands dirigeants. "Le sportif, le philosophe, le dirigeant: Bernard Jeu", reprend ses articles les pls significatfs.

Physicians and patients rely on medical journals as trusted sources of medical information. Unfortunately, conflicts of interest may undermine the credibility of the medical literature. Improved policies and practices at journals should address the conflicts of interest of authors, reviewers, editors, and journals. Medical journals should manage and eliminate conflicts, not just improve the disclosure of financial relationships.

This book explores the shift in sociology away from the shared aspiration of the classical transition, of transcending partiality through the construction of a "science of society", in the face of challenges to the notion of objectivity. With the increasing subjugation of sociology to political ideologies and a growing emphasis on "policy", which casts sociology in the role of a provider of intellectual content for political programs, this volume asks whether the situation is the result of an exhaustion of ideas (...) or might perhaps be rooted in the failure in the very program of establishing sociology as a science. Taking seriously the challenges to the classical aspiration of constructing theories that both explain and are grounded in empirical reality, The Future of Sociology asks whether the core idea of transcending ideology is still worth pursuing, and whether there remains scope for making sociology scientific. As such, it will appeal to scholars and students of sociology, social theory, and social scientific methodology. (shrink)

Academic philosophy can be puzzling to newcomers. The conventions, terms, and expectations entrenched among philosophers aren’t always clear from the outside. Why are philosophers so preoccupied with finding “the truth”—doesn’t everyone have their own philosophy? Is philosophy so deep and difficult that its literature has to be incomprehensible? What kinds of arguments can there be for a philosophical position? Where does the evidence come from? Why is there so much jargon—wouldn’t it be better to do away with it altogether? Best-selling (...) author and retired philosophy professor Robert Martin answers these questions and many more, offering a practical guide to arguing and writing philosophically. Anecdotes, jokes, asides, digressions, oddments, and entertainments are included throughout, resulting in an informal introduction that doesn’t shy away from the nuts and bolts of philosophical argument. (shrink)